POLR3K Protein (AA 1-108, full length) (His-SUMO Tag)
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- 抗原 See all POLR3K 蛋白
- POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
- 蛋白类型
- Recombinant
- 产品特性
- full length, AA 1-108
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This POLR3K protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MLLFCPGCGN GLIVEEGQRC HRFACNTCPY VHNITRKVTN RKYPKLKEVD DVLGGAAAWE NVDSTAESCP KCEHPRAYFM QLQTRSADEP MTTFYKCCNA QCGHRWRD
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product POLR3K 蛋白
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Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K) (AA 1-108) protein (His tag)
POLR3K 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K) (AA 1-108) protein (GST tag)POLR3K 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K) (AA 1-108) protein (Strep Tag)Crystallography grade POLR3K 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K) (AA 1-108) protein (Strep Tag)Crystallography grade POLR3K 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K) (AA 1-108), (full length) protein (His-SUMO Tag)POLR3K 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K) protein (Myc-DYKDDDDK Tag)POLR3K 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
- 别名
- RPC10 (POLR3K 产品)
- 别名
- MGC108467 Protein, POLR3K Protein, 12.3kDa Protein, 1500004O14Rik Protein, AI196849 Protein, AU014893 Protein, C11 Protein, RPC10 Protein, RPC11 Protein, C11-RNP3 Protein, RPC12.5 Protein, hRPC11 Protein, RNA polymerase III subunit K Protein, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa S homeolog Protein, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa Protein, polymerase (RNA) III (DNA directed) polypeptide K Protein, Polr3k Protein, polr3k.S Protein, polr3k Protein, POLR3K Protein
- 背景
- DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as tplate for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway .
- 分子量
- 28.3 kDa
- UniProt
- Q9Y2Y1
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