PABP Protein (AA 1-370, partial) (His-SUMO Tag)
-
- 抗原 See all PABP (PABPC1) 蛋白
- PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-370, partial
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This PABP protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MNPSAPSYPM ASLYVGDLHP DVTEAMLYEK FSPAGPILSI RVCRDMITRR SLGYAYVNFQ QPADAERALD TMNFDVIKGK PVRIMWSQRD PSLRKSGVGN IFIKNLDKSI DNKALYDTFS AFGNILSCKV VCDENGSKGY GFVHFETQEA AERAIEKMNG MLLNDRKVFV GRFKSRKERE AELGARAKEF TNVYIKNFGE DMDDERLKDL FGKFGPALSV KVMTDESGKS KGFGFVSFER HEDAQKAVDE MNGKELNGKQ IYVGRAQKKV ERQTELKRKF EQMKQDRITR YQGVNLYVKN LDDGIDDERL RKEFSPFGTI TSAKVMMEGG RSKGFGFVCF SSPEEATKAV TEMNGRIVAT KPLYVALAQR
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product PABPC1 蛋白
-
Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (AA 1-636) protein (GST tag)
PABPC1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (AA 2-235) protein (His-IF2DI Tag)PABPC1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) protein (Myc-DYKDDDDK Tag)PABPC1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- 抗原
- PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
- 别名
- PABP1 (PABPC1 产品)
- 别名
- PAB1 Protein, PABP Protein, PABP1 Protein, PABPC2 Protein, PABPL1 Protein, Pabp1 Protein, PabpI Protein, Pabpl1 Protein, ePAB Protein, Pabp Protein, pab1 Protein, pabp Protein, pabp1 Protein, pabpc1 Protein, pabpc2 Protein, PABPC1 Protein, wu:fb16a02 Protein, wu:fi19b08 Protein, wu:fj12d09 Protein, wu:fj61f06 Protein, zgc:109879 Protein, zgc:77608 Protein, poly(A) binding protein cytoplasmic 1 Protein, poly(A) binding protein, cytoplasmic 1 Protein, poly(A) binding protein, cytoplasmic 1 S homeolog Protein, poly(A) binding protein cytoplasmic 1 like Protein, poly(A) binding protein, cytoplasmic 1 L homeolog Protein, poly(A) binding protein, cytoplasmic 1a Protein, poly A binding protein, cytoplasmic 1 b Protein, PABPC1 Protein, Pabpc1 Protein, pabpc1.S Protein, pabpc1 Protein, PABPC1L Protein, pabpc1.L Protein, pabpc1a Protein, pabpc1b Protein
- 背景
- Binds the poly(A) tail of mRNA, including that of its own transcript. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Involved in regulation of nonsense-mediated decay (NMD) of mRNAs containing prature stop codons, for the recognition of prature termination codons (PTC) and initiation of NMD a competitive interaction between UPF1 and PABPC1 with the ribosome-bound release factors is proposed.
- 分子量
- 57.8 kDa
- UniProt
- P11940
- 途径
- SARS-CoV-2 Protein Interactome
-
