OLR1 Protein (AA 58-273, Extracellular) (His tag)
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- 抗原 See all OLR1 蛋白
- OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))
- 蛋白类型
- Recombinant
- 产品特性
- Extracellular, AA 58-273
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This OLR1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MQLSQVSDLL TQEQANLTHQ KKKLEGQISA RQQAEEASQE SENELKEMIE TLARKLNEKS KEQMELHHQN LNLQETLKRV ANCSAPCPQD WIWHGENCYL FSSGSFNWEK SQEKCLSLDA KLLKINSTAD LDFIQQAISY SSFPFWMGLS RRNPSYPWLW EDGSPLMPHL FRVRGAVSQT YPSGTCAYIQ RGAVYAENCI LAAFSICQKK ANLRAQ
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product OLR1 蛋白
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Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 60-363) protein (His tag)
OLR1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 61-273) protein (His tag)OLR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 58-273) proteinOLR1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) protein (His tag)OLR1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 1-273) protein (GST tag)OLR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) protein (Fc Tag)OLR1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant (90.4+8.5) % as determined by SDS-PAGE
Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 1-273) protein (Strep Tag)Crystallography grade OLR1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 1-363) protein (Strep Tag)Crystallography grade OLR1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 58-273) protein (His tag)Crystallography grade OLR1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) (AA 55-363) protein (His tag)Crystallography grade OLR1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))
- 别名
- OLR1 (OLR1 产品)
- 别名
- OLR1 Protein, LOX1 Protein, Olr1 Protein, CLEC8A Protein, LOXIN Protein, SCARE1 Protein, SLOX1 Protein, LOX-1 Protein, SR-EI Protein, Scare1 Protein, Oldlr1 Protein, Oldr1 Protein, PLOX-1 Protein, oxidized low density lipoprotein receptor 1 Protein, oxidized low density lipoprotein (lectin-like) receptor 1 Protein, OLR1 Protein, Olr1 Protein
- 背景
- Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.
- 分子量
- 28.8 kDa
- UniProt
- P78380
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