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NPHP1 Protein (AA 1-109, partial) (GST tag)

NPHP1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5710019
发货至: 中国
  • 抗原 See all NPHP1 蛋白
    NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-109, partial
    宿主
    • 3
    • 1
    资源
    • 2
    • 2
    大肠杆菌(E. Coli)
    标记
    This NPHP1 protein is labelled with GST tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MLARRQRDPL QALRRRNQEL KQQVDSLLSE SQLKEALEPN KRQHIYQRCI QLKQAIDENK NALQKLSKAD ESAPVANYNQ RKEEEHTLLD KLTQQLQGLA VTISRENITE
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product NPHP1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))
    别名
    NPHP1 (NPHP1 产品)
    别名
    JBTS4 Protein, NPH1 Protein, SLSN1 Protein, nephrocystin-1 Protein, NPHP1 Protein, im:7162391 Protein, wu:fi59g07 Protein, zgc:152930 Protein, Nphp1 Protein, nephrocystin 1 Protein, nephronophthisis 1 (juvenile) homolog (human) Protein, nephronophthisis 1 (juvenile) L homeolog Protein, nephronophthisis 1 Protein, nephrocystin-1 Protein, NPHP1 Protein, Nphp1 Protein, nphp1.L Protein, nphp1 Protein, LOC100725987 Protein
    背景
    Together with BCAR1 it may play a role in the control of epithelial cell polarity. Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 . Does not se to be strictly required for ciliogenesis . Ses to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling. May play a role in the regulation of intraflagellar transport (IFT) during cilia assbly. Required for normal retina development. In connecting photoreceptor cilia influences the movent of some IFT proteins such as IFT88 and WDR19. Involved in spermatogenesis .
    分子量
    40.3 kDa
    UniProt
    O15259
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