NANOS2 Protein (AA 1-138, full length) (His-SUMO Tag)
-
- 抗原 See all NANOS2 蛋白
- NANOS2 (Nanos Homolog 2 (NANOS2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-138, full length
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This NANOS2 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MQLPPFDMWK DYFNLSQVVW ALIASRGQRL ETQEIEEPSP GPPLGQDQGL GAPGANGGLG TLCNFCKHNG ESRHVYSSHQ LKTPDGVVVC PILRHYVCPV CGATGDQAHT LKYCPLNGGQ QSLYRRSGRN SAGRRVKR
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product NANOS2 蛋白
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- 抗原
- NANOS2 (Nanos Homolog 2 (NANOS2))
- 别名
- NANO2 (NANOS2 产品)
- 别名
- NOS2 Protein, RGD1562436 Protein, nos2 Protein, nanos C2HC-type zinc finger 2 Protein, nanos homolog 2 (Drosophila) Protein, nanos 2 Protein, nanos2 protein Protein, NANOS2 Protein, Nanos2 Protein, nanos2 Protein
- 背景
- Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the fale fate. Represses the fale fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for preiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial st cell population. Not essential for the assbly of P-bodies but is required for the maintenance of their normal state .
- 分子量
- 31.1 kDa
- UniProt
- P60321
- 途径
- Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
-