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KCNAB2 Protein (AA 1-367, full length) (His-SUMO Tag)

KCNAB2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5709787
发货至: 中国
  • 抗原 See all KCNAB2 蛋白
    KCNAB2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 2 (KCNAB2))
    蛋白类型
    Recombinant
    产品特性
    AA 1-367, full length
    宿主
    • 5
    • 1
    • 1
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This KCNAB2 protein is labelled with His-SUMO Tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MYPESTTGSP ARLSLRQTGS PGMIYSTRYG SPKRQLQFYR NLGKSGLRVS CLGLGTWVTF GGQITDEMAE QLMTLAYDNG INLFDTAEVY AAGKAEVVLG NIIKKKGWRR SSLVITTKIF WGGKAETERG LSRKHIIEGL KASLERLQLE YVDVVFANRP DPNTPMEETV RAMTHVINQG MAMYWGTSRW SSMEIMEAYS VARQFNLTPP ICEQAEYHMF QREKVEVQLP ELFHKIGVGA MTWSPLACGI VSGKYDSGIP PYSRASLKGY QWLKDKILSE EGRRQQAKLK ELQAIAERLG CTLPQLAIAW CLRNEGVSSV LLGASNADQL MENIGAIQVL PKLSSSIIHE IDSILGNKPY SKKDYRS
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product KCNAB2 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    KCNAB2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 2 (KCNAB2))
    别名
    KCAB2 (KCNAB2 产品)
    别名
    kcnab2 Protein, KCNAB2 Protein, DKFZp459E056 Protein, akr6a5 Protein, kcna2b Protein, kvb-a Protein, kvb2 Protein, kvbeta2 Protein, kvbeta2.1 Protein, kvbeta2.2 Protein, AKR6A5 Protein, HKvbeta2 Protein, HKvbeta2.1 Protein, HKvbeta2.2 Protein, KCNA2B Protein, KV-BETA-2 Protein, Kvbeta2.1 Protein, F5 Protein, I2rf5 Protein, Kcnb3 Protein, kv-beta-2 Protein, potassium channel, voltage gated subfamily A regulatory beta subunit 1 Protein, potassium voltage-gated channel subfamily A regulatory beta subunit 2 Protein, potassium voltage-gated channel, shaker-related subfamily, beta member 2 a Protein, potassium channel, voltage gated subfamily A regulatory beta subunit 2 L homeolog Protein, voltage-gated potassium channel subunit beta-2 Protein, potassium voltage-gated channel, shaker-related subfamily, beta member 2 Protein, kcnab1 Protein, KCNAB2 Protein, kcnab2a Protein, kcnab2.L Protein, LOC397248 Protein, Kcnab2 Protein
    背景
    Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits . Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability . Promotes expression of the pore-forming alpha subunits at the cell mbrane, and thereby increases channel activity . Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore . Promotes KCNA4 channel closure . Modulates the functional properties of KCNA5 . Enhances KCNB2 channel activity . Binds NADPH and has NADPH-dependent aldoketoreductase activity . Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro) .
    分子量
    56.97 kDa
    UniProt
    Q13303
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