IRF8 Protein (AA 1-424, full length) (His-SUMO Tag)
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- 抗原 See all IRF8 蛋白
- IRF8 (Interferon Regulatory Factor 8 (IRF8))
- 蛋白类型
- Recombinant
- 产品特性
- full length, AA 1-424
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宿主
- 小鼠
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资源
- 大肠杆菌(E. Coli)
- 标记
- This IRF8 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MCDRNGGRRL RQWLIEQIDS SMYPGLIWEN DEKTMFRIPW KHAGKQDYNQ EVDASIFKAW AVFKGKFKEG DKAEPATWKT RLRCALNKSP DFEEVTDRSQ LDISEPYKVY RIVPEEEQKC KLGVAPAGCM SEVPEMECGR SEIEELIKEP SVDEYMGMTK RSPSPPEACR SQILPDWWVQ QPSAGLPLVT GYAAYDTHHS AFSQMVISFY YGGKLVGQAT TTCLEGCRLS LSQPGLPKLY GPDGLEPVCF PTADTIPSER QRQVTRKLFG HLERGVLLHS NRKGVFVKRL CQGRVFCSGN AVVCKGRPNK LERDEVVQVF DTNQFIRELQ QFYATQSRLP DSRVVLCFGE EFPDTVPLRS KLILVQVEQL YARQLVEEAG KSCGAGSLMP ALEEPQPDQA FRMFPDICTS HQRPFFRENQ QITV
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product IRF8 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- IRF8 (Interferon Regulatory Factor 8 (IRF8))
- 别名
- IRF8 (IRF8 产品)
- 别名
- zgc:92252 Protein, IRF8 Protein, MGC140338 Protein, DKFZp469B0320 Protein, H-ICSBP Protein, ICSBP Protein, ICSBP1 Protein, IRF-8 Protein, icsbp1 Protein, AI893568 Protein, Icsbp1 Protein, Myls Protein, interferon regulatory factor 8 Protein, interferon regulatory factor 8 L homeolog Protein, irf8 Protein, IRF8 Protein, irf8.L Protein, Irf8 Protein
- 背景
- Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune syst. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory elent, followed by cooperative binding of BATF and IRF8 and activation of genes.
- 分子量
- 64.21 kDa
- UniProt
- P23611
- 途径
- Cellular Response to Molecule of Bacterial Origin
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