Id2 Protein (AA 1-134, full length) (His-SUMO Tag)
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- 抗原 See all Id2 蛋白
- Id2 (Inhibitor of DNA Binding 2 (Id2))
- 蛋白类型
- Recombinant
- 产品特性
- full length, AA 1-134
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This Id2 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product Id2 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- Id2 (Inhibitor of DNA Binding 2 (Id2))
- 别名
- ID2 (Id2 产品)
- 别名
- AI255428 Protein, C78922 Protein, Idb2 Protein, bHLHb26 Protein, Ac2-300 Protein, GIG8 Protein, ID2A Protein, ID2H Protein, XId2 Protein, id2-A Protein, inhibitor of DNA binding 2 Protein, inhibitor of DNA binding 2, HLH protein Protein, inhibitor of DNA binding 2 L homeolog Protein, Id2 Protein, ID2 Protein, id2.L Protein
- 背景
- Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
- 分子量
- 30.9 kDa
- UniProt
- Q02363
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