FOXP1 Protein (AA 1-114, partial) (GST tag)
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- 抗原 See all FOXP1 蛋白
- FOXP1 (Forkhead Box P1 (FOXP1))
- 蛋白类型
- Recombinant
- 产品特性
- partial, AA 1-114
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This FOXP1 protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MMQESGTETK SNGSAIQNGS GGSNHLLECG GLREGRSNGE TPAVDIGAAD LAHAQQQQQQ WHLINHQPSR SPSSWLKRLI SSPWELEVLQ VPLWGAVAET KMSGPVCQPN PSPF
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product FOXP1 蛋白
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Forkhead Box P1 (FOXP1) (AA 1-114) protein (GST tag)
FOXP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Forkhead Box P1 (FOXP1) (AA 1-677) protein (Strep Tag)Crystallography grade FOXP1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Forkhead Box P1 (FOXP1) (AA 1-705) protein (Strep Tag)Crystallography grade FOXP1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Forkhead Box P1 (FOXP1) protein (DYKDDDDK Tag)FOXP1 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Forkhead Box P1 (FOXP1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)FOXP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- FOXP1 (Forkhead Box P1 (FOXP1))
- 别名
- FOXP1 (FOXP1 产品)
- 别名
- 12CC4 Protein, QRF1 Protein, hFKH1B Protein, 3110052D19Rik Protein, 4932443N09Rik Protein, AI461938 Protein, AW494214 Protein, foxp1 Protein, im:7139058 Protein, wu:fc83a06 Protein, FOXP1 Protein, MGC145686 Protein, 12cc4 Protein, fkh1b Protein, hspc215 Protein, qrf1 Protein, xlfoxp1 Protein, im:7146611 Protein, wu:fb97f01 Protein, zgc:154010 Protein, forkhead box P1 Protein, forkhead box P1b Protein, forkhead box P1 S homeolog Protein, forkhead box P1a Protein, FOXP1 Protein, Foxp1 Protein, foxp1b Protein, foxp1 Protein, foxp1.S Protein, foxp1a Protein
- 背景
- Transcriptional repressor . Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential . Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program, the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development. Involved in regulation of cardiac muscle cell proliferation. Involved in the columnar organization of spinal motor neurons. Promotes the formation of the lateral motor neuron column (LMC) and the preganglionic motor column (PGC) and is required for respective appropriate motor axon projections. The segment-appropriate generation of spinal chord motor columns requires cooperation with other Hox proteins. Can regulate PITX3 promoter activity, may promote midbrain identity in bryonic st cell-derived dopamine neurons by regulating PITX3. Negatively regulates the differentiation of T follicular helper cells T(FH)s. Involved in maintainance of hair follicle st cell quiescence, the function probably involves regulation of FGF18 . Represses transcription of various pro-apoptotic genes and cooperates with NF-kappa B-signaling in promoting B-cell expansion by inhibition of caspase-dependent apoptosis . Binds to CSF1R promoter elents and is involved in regulation of monocyte differentiation and macrophage functions, repression of CSF1R in monocytes ses to involve NCOR2 as corepressor . Involved in endothelial cell proliferation, tube formation and migration indicative for a role in angiogenesis, the role in neovascularization ses to implicate suppression of SA5B . Can negatively regulate androgen receptor signaling .
- 分子量
- 39.6 kDa
- UniProt
- Q9H334
- 途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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