ETHE1 Protein (AA 8-254) (His-SUMO Tag)
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- 抗原 See all ETHE1 蛋白
- ETHE1 (Ethylmalonic Encephalopathy 1 (ETHE1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 8-254
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This ETHE1 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- VARRQLSQRG GSGAPILLRQ MFEPVSCTFT YLLGDRESRE AVLIDPVLET APRDAQLIKE LGLRLLYAVN THCHADHITG SGLLRSLLPG CQSVISRLSG AQADLHIEDG DSIRFGRFAL ETRASPGHTP GCVTFVLNDH SMAFTGDALL IRGCGRTDFQ QGCAKTLYHS VHEKIFTLPG DCLIYPAHDY HGFTVSTVEE ERTLNPRLTL SCEEFVKIMG NLNLPKPQQI DFAVPANMRC GVQTPTA
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product ETHE1 蛋白
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Ethylmalonic Encephalopathy 1 (ETHE1) (AA 13-254) protein (His tag)
ETHE1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Ethylmalonic Encephalopathy 1 (ETHE1) (AA 1-254) protein (GST tag)ETHE1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ethylmalonic Encephalopathy 1 (ETHE1) (AA 155-254) protein (GST tag)ETHE1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ethylmalonic Encephalopathy 1 (ETHE1) protein (Myc-DYKDDDDK Tag)ETHE1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- ETHE1 (Ethylmalonic Encephalopathy 1 (ETHE1))
- 别名
- ETHE1 (ETHE1 产品)
- 别名
- zgc:85680 Protein, HSCO Protein, YF13H12 Protein, 0610025L15Rik Protein, Hsco Protein, ETHE1, persulfide dioxygenase Protein, ethylmalonic encephalopathy 1 Protein, Ethe1 Protein, ethe1 Protein, ETHE1 Protein
- 背景
- Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H2S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H2S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus .
- 分子量
- 43.08 kDa
- UniProt
- O95571
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