AGRP Protein (AA 21-132) (His-SUMO Tag)
-
- 抗原 See all AGRP 蛋白
- AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-132
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This AGRP protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- AQMGLAPMEG IRRPDQALLP ELPGLGLRAP LKKTTAEQAE EDLLQEAQAL AEVLDLQDRE PRSSRRCVRL HESCLGQQVP CCDPCATCYC RFFNAFCYCR KLGTAMNPCS RT
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product AGRP 蛋白
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- 抗原
- AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
- 别名
- AGRP (AGRP 产品)
- 别名
- AGRT Protein, ART Protein, ASIP2 Protein, Agrt Protein, Art Protein, agouti related neuropeptide Protein, agouti-related protein pseudogene Protein, AGRP Protein, Agrp Protein, LOC100352591 Protein
- 背景
- Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin syst. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R . Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
- 分子量
- 28.5 kDa
- UniProt
- O00253
- 途径
- Feeding Behaviour, Photoperiodism
-