CD200R1 Protein (AA 27-266) (Fc Tag,AVI tag,Biotin)
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- 抗原 See all CD200R1 蛋白
- CD200R1 (CD200 Receptor 1 (CD200R1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 27-266
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD200R1 protein is labelled with Fc Tag,AVI tag,Biotin.
- 品牌
- PrecisionAvi
- 序列
- AA 27-266
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 55.8 kDa. The protein migrates as 70-115 KDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by reduced SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product CD200R1 蛋白
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CD200 Receptor 1 (CD200R1) protein (His-Avi Tag,Biotin)
CD200R1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
CD200 Receptor 1 (CD200R1) protein (His-Avi Tag)CD200R1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
CD200 Receptor 1 (CD200R1) (AA 27-266) protein (Fc Tag)CD200R1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD200 Receptor 1 (CD200R1) (AA 26-238) protein (His tag)CD200R1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD200 Receptor 1 (CD200R1) (AA 25-267) protein (His tag)CD200R1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD200 Receptor 1 (CD200R1) (AA 1-348) protein (GST tag)CD200R1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
CD200 Receptor 1 (CD200R1) (AA 73-172) protein (GST tag)CD200R1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
CD200 Receptor 1 (CD200R1) (Active) protein (His tag,Fc Tag)CD200R1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
CD200 Receptor 1 (CD200R1) (Active) protein (His tag)CD200R1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
CD200 Receptor 1 (CD200R1) (AA 29-243) protein (His tag)Crystallography grade CD200R1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- CD200R1 (CD200 Receptor 1 (CD200R1))
- 别名
- CD200 R1 (CD200R1 产品)
- 别名
- CD200R Protein, HCRTR2 Protein, MOX2R Protein, OX2R Protein, Mox2r Protein, CD200R1 Protein, CD200R2 Protein, CD200R-B1V1 Protein, CD200R1A Protein, CD200 receptor 1 Protein, cell surface glycoprotein CD200 receptor 1 Protein, CD200 receptor 1-like Protein, CD200R1 Protein, Cd200r1 Protein, LOC487977 Protein, CD200R1L Protein
- 背景
- Cell surface glycoprotein CD200 receptor 1 is a protein that in humans is encoded by the CD200R1 gene. This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. CD200 and its receptor CD200R are both type-1 membrane glycoproteins, which are members of the immunoglobulin superfamily (IgSF). Besides the inhibitory effect on macrophages, CD200/CD200R also play an important role in regulating the regulatory T cells, allergicreaction, autoimmune diseases, allograft, neurological diseases and other autoimmune-related diseases. The interaction between CD200, which is mainly present in neurons but also in astrocytes, and CD200R1, which is mainly present in microglia, is one of the mechanisms involved in keeping the microglial proinflammatory phenotype under control in physiological conditions. Alterations in the expression of CD200 and CD200R1 have been described in neurodegenerative diseases, but little is known about the mechanism of regulation of these proteins under physiological or pathological conditions.
- 分子量
- 55.8 kDa
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