IL1F10 Protein (AA 20-152) (His tag)
-
- 抗原 See all IL1F10 蛋白
- IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-152
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This IL1F10 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 人
- 产品特性
- Human IL-38 (aa Leu20-Trp152) is fused at the C-terminus to a His-tag.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IL1F10 蛋白
-
Interleukin 1 Family, Member 10 (Theta) (IL1F10) (AA 1-152) protein (His tag)
IL1F10 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 1 Family, Member 10 (Theta) (IL1F10) (AA 1-152) protein (Strep Tag)Crystallography grade IL1F10 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Interleukin 1 Family, Member 10 (Theta) (IL1F10) (AA 1-152) protein (Strep Tag)Crystallography grade IL1F10 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Solid
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
-
- 抗原
- IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))
- 别名
- IL-38 (IL1F10 产品)
- 别名
- FIL1-theta Protein, IL-1HY2 Protein, IL-38 Protein, IL1-theta Protein, IL1HY2 Protein, interleukin 1 family, member 10 Protein, interleukin 1 family member 10 Protein, Il1f10 Protein, IL1F10 Protein
- 背景
- IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F family such as IL-1F5 / 6 / 8 or 9 (also called IL-36Ra, IL-36alpha, IL-36beta or IL-36gamma) is important to increase their biological activity. Recently it has been shown that IL-38 is N-terminally processed and secreted by apoptotic cells. Released processed IL-38 (20-152) binds to the receptor Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1, TIGIRR-2) at the surface of macrophages. Processed IL-38-activated IL1RAPL1 reduces the production of IL-6 leading to inflammation attenuation. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.
- 分子量
- ~16kDa
- UniProt
- Q8WWZ1
-
