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NMNAT2 Protein (AA 2-307) (His tag)

NMNAT2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >90 % (SDS-PAGE) SDS
产品编号 ABIN5564378
发货至: 中国
  • 抗原 See all NMNAT2 蛋白
    NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
    蛋白类型
    Recombinant
    产品特性
    AA 2-307
    宿主
    • 7
    • 1
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    • 1
    资源
    • 4
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    大肠杆菌(E. Coli)
    标记
    This NMNAT2 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    交叉反应
    产品特性
    Human NMNA2 (aa 2-307) is fused at the N-terminus to a His-tag.
    纯度
    >90 % (SDS-PAGE)
    Top Product
    Discover our top product NMNAT2 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Solid
    浓度
    Lot specific
    缓冲液
    Lyophilized in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl plus 0.025 % CHAPS.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    有效期
    6 months
  • 抗原
    NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
    别名
    NMNAT2 (NMNAT2 产品)
    别名
    zgc:73048 Protein, wu:fj59g01 Protein, NMNAT2 Protein, C1orf15 Protein, PNAT2 Protein, AI843915 Protein, D030041I09Rik Protein, PNAT1 Protein, nicotinamide nucleotide adenylyltransferase 2 Protein, nmnat2 Protein, NMNAT2 Protein, Nmnat2 Protein
    背景
    Nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. NMNAT2 also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. It is highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. NMNAT2 is also found in the heart, skeletal muscle, pancreas and islets of Langerhans. NMNAT2 is essential for axon growth and survival. Its loss from injured axons may activate Wallerian degeneration (axon degeneration induced by nerve injury), whereas NMNAT overexpression rescues axons from degeneration.
    分子量
    ~35kDa (SDS-PAGE)
    UniProt
    Q9BZQ4
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