FNDC4 Protein (AA 41-163, Extracellular Domain)
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- 抗原 See all FNDC4 蛋白
- FNDC4 (Fibronectin Type III Domain Containing 4 (FNDC4))
- 蛋白类型
- Recombinant
- 产品特性
- AA 41-163, Extracellular Domain
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宿主
- 人, 小鼠, 大鼠, 犬, 猴
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 犬, 人, 猴, 小鼠, 大鼠
- 产品特性
- FNDC4 (extracellular domain, human (aa 45-167) / mouse (aa 41-163)) is untagged. FNDC4 extracellular domain has 100 % identity between human, mouse, rat, dog and monkey.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FNDC4 蛋白
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Fibronectin Type III Domain Containing 4 (FNDC4) (AA 45-148) protein (His-IF2DI Tag)
FNDC4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Fibronectin Type III Domain Containing 4 (FNDC4) (AA 1-234) protein (GST tag)FNDC4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Fibronectin Type III Domain Containing 4 (FNDC4) (AA 45-154) protein (GST tag)FNDC4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Fibronectin Type III Domain Containing 4 (FNDC4) protein (Myc-DYKDDDDK Tag)FNDC4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Solid
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- FNDC4 (Fibronectin Type III Domain Containing 4 (FNDC4))
- 别名
- FNDC4 (FNDC4 产品)
- 别名
- 2810430J06Rik Protein, 6330410H20Rik Protein, AB030187 Protein, AI838506 Protein, AW487863 Protein, FRCP1 Protein, Fnmp1 Protein, FNDC4 Protein, fibronectin type III domain containing 4 Protein, Fndc4 Protein, FNDC4 Protein, fndc4 Protein
- 背景
- Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. FNDC4 is an ortholog of FNDC5 with 50 % identity and 86 % similarity compared to Irisin. FNDC4 as well as FNDC5 are extremely well conserved between species. The function of FNDC4 is unknown. The human FNDC4 gene is highly enriched in liver, brain tissue and adipocytes.
- 分子量
- ~16kDa
- UniProt
- Q9H6D8
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