Insulin Receptor Protein (INSR) (DYKDDDDK-His Tag)
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- 抗原 See all Insulin Receptor (INSR) 蛋白
- Insulin Receptor (INSR)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Insulin Receptor protein is labelled with DYKDDDDK-His Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human CD220 / INSR (C-term DDK/His tag, transcript variant 1) protein expressed in Human HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product INSR 蛋白
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Insulin Receptor (INSR) (AA 28-944) (Active) protein (His tag)
INSR 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Insulin Receptor (INSR) (AA 881-980) protein (GST tag)INSR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin Receptor (INSR) (Active) protein (GST tag,His tag)INSR 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE. Active
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 1 x PBS, pH 7.4, 10 % glycerol
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- Insulin Receptor (INSR)
- 别名
- CD220 / INSR (INSR 产品)
- 背景
- This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
- 分子量
- 25 kDa
- NCBI登录号
- NP_000199
- 途径
- NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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