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Transferrin Receptor 2 Protein (TFR2) (AA 103-798) (Fc Tag)

TFR2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func
产品编号 ABIN4949192
发货至: 中国
  • 抗原 See all Transferrin Receptor 2 (TFR2) 蛋白
    Transferrin Receptor 2 (TFR2)
    蛋白类型
    Recombinant
    产品特性
    AA 103-798
    宿主
    • 7
    • 5
    • 2
    小鼠
    资源
    • 7
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This Transferrin Receptor 2 protein is labelled with Fc Tag.
    应用范围
    Functional Studies (Func)
    序列
    AA 103-798
    产品特性
    This protein carries a mouse IgG1 Fc tag at the N-terminus, and has a calculated MW of 103.2 kDa. The predicted N-terminus is Ile. The reducing (R) protein migrates as 116 kDa in SDS-PAGE due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 0.1 EU per μg by the LAL method.
    Top Product
    Discover our top product TFR2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • Stocki, Szary, Rasmussen, Demydchuk, Northall, Logan, Gauhar, Thei, Moos, Walsh, Rutkowski: "Blood-brain barrier transport using a high affinity, brain-selective VNAR antibody targeting transferrin receptor 1." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 35, Issue 2, pp. e21172, (2021) (PubMed).

  • 抗原
    Transferrin Receptor 2 (TFR2)
    别名
    Transferrin R2 (TFR2 产品)
    别名
    TFR2 Protein, Trfr2 Protein, HFE3 Protein, TFRC2 Protein, zgc:123043 Protein, transferrin receptor 2 Protein, TFR2 Protein, Tfr2 Protein, tfr2 Protein
    背景
    Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.
    分子量
    101.1 kDa
    NCBI登录号
    NP_056614
    UniProt
    Q9JKX3
    途径
    Transition Metal Ion Homeostasis
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