(1 reference)-
- 抗原 See all ELAVL4 蛋白
- ELAVL4 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D) (ELAVL4))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This ELAVL4 protein is labelled with His tag.
- 应用范围
- ELISA, Western Blotting (WB)
- 纯化方法
- Expressed in E.Coli and purified by affinity chromatography
- 纯度
- > 95%
- 内毒素水平
- less than 0.1 ng/µg (1 IEU/µg)
- Top Product
- Discover our top product ELAVL4 蛋白
-
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D) (ELAVL4) (AA 312-380) protein (GST tag)
ELAVL4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D) (ELAVL4) (AA 1-385) protein (Strep Tag)Crystallography grade ELAVL4 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D) (ELAVL4) (AA 1-380) protein (His tag)Crystallography grade ELAVL4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D) (ELAVL4) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ELAVL4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- 应用备注
- Detection of anti-Hu paraneoplastic antibodies via WB or ELISA assay. Identification of regulatory elements in mRNA.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Storage buffer PBS, pH 7.2
- 储存条件
- -20 °C
- 储存方法
- Heat stable , shipped at ambient temp. Upon delivery aliquot and store in fridge , longterm storage at -20°C.
-
-
: "Purification and properties of HuD, a neuronal RNA-binding protein." in: The Journal of biological chemistry, Vol. 271, Issue 19, pp. 11518-24, (1996) (PubMed).
-
: "Purification and properties of HuD, a neuronal RNA-binding protein." in: The Journal of biological chemistry, Vol. 271, Issue 19, pp. 11518-24, (1996) (PubMed).
-
- 抗原
- ELAVL4 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D) (ELAVL4))
- 别名
- ELAV-like protein 4 (ELAVL4 产品)
- 别名
- HUD Protein, PNEM Protein, HuD Protein, RGD1561943 Protein, r-HuD Protein, elrd Protein, hud Protein, wu:fc24h01 Protein, Elav Protein, Hud Protein, elrD Protein, elrD1 Protein, elrD2 Protein, ELAV-like protein 4 Protein, ELAV like RNA binding protein 4 Protein, ELAV like neuron-specific RNA binding protein 4 Protein, ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) Protein, ELAV like neuron-specific RNA binding protein 4 L homeolog Protein, LOC100282339 Protein, LOC100284149 Protein, ELAVL4 Protein, Elavl4 Protein, elavl4 Protein, elavl4.L Protein
- 背景
-
HuD otherwise known as ELAV-like protein 4 is a protein that in humans is encoded by the ELAVL4 gene.
The HuD/ELAVL4 protein is an RNA-binding protein.
HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the half-life of the transcript is increased. HuD is important in neurons during brain development and plasticity.
HuD was originaly discovered as the paraneoplastic antigen expressed in neuroendocrine tumors. Recombinant HuD was first used to assay the presence of anti-Hu antibodies and thereby diagnose the presence of small cell lung cancer and subacute sensory neuronopathy. In normal cells , it functions to regulate gene expression and the recombinant protein has been used to identify regualtory elements in mRNA. - 分子量
- 66 kDa
-
You are here:
