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LILRB2 Protein (AA 22-461) (Fc Tag,AVI tag,Biotin)

LILRB2 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN3137681
发货至: 中国
  • 抗原 See all LILRB2 蛋白
    LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 22-461
    宿主
    • 19
    • 2
    资源
    • 14
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This LILRB2 protein is labelled with Fc Tag,AVI tag,Biotin.
    序列
    AA 22-461
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    产品特性
    High Quality Authentic Human LILRB2 Protein
    • The production of this recombinant, biotinylated LILRB2 protein is carried out using a proprietary expression platform.
    • As expression hosts, the human HEK293 cells have a variety of advantages compared to other cell types.
    • Most importantly, the proteins retain their authentic post-translational processing, which often translates into high bioactivity and stability.
    High Bioactivity & Detection Sensitivity
    • The bioactivity of biotinylated proteins is determined both by the structure of the protein itself, and by the way how biotinylation is performed.
    • For every single protein, multiple options of tags and biotinylation methods are tested and the products are evaluated in a variety of binding assays.
    • Only those with the best performance are selected for production.
    Low Batch-to-Batch Variation
    • Products are routinely tested using rigorous quality control measures to ensure consistent performance.
    • Newly produced products are subjected to side-by-side comparison with our internal standard in a variety of assays.
    • Only those within an acceptable margin of difference are allowed to be released.
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product LILRB2 蛋白
  • 说明

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
    别名
    LILRB2 (LILRB2 产品)
    别名
    CD85D Protein, ILT-4 Protein, ILT4 Protein, LIR-2 Protein, LIR2 Protein, MIR-10 Protein, MIR10 Protein, leukocyte immunoglobulin-like receptor subfamily A member 3 Protein, leukocyte immunoglobulin like receptor B2 Protein, LOC100433990 Protein, LILRB2 Protein
    背景
    Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
    分子量
    76.2 kDa
    途径
    Cellular Response to Molecule of Bacterial Origin
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