PARP3 Protein (HA tag,His tag)
-
- 抗原 See all PARP3 蛋白
- PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 宿主
- 人
-
资源
- Insect cells (Sf21)
- 标记
- This PARP3 protein is labelled with HA tag,His tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 人
- 产品特性
- Human full-length PARP-3 [ARTD3] is fused to a HA-tag and a His-tag.
- 纯度
- >98 % (SDS-PAGE)
- Top Product
- Discover our top product PARP3 蛋白
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
-
>10U/mg protein (only monoADP-ribosyl transferase activity).
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride and 50 mM imidazole, 0.2 % NP-40 and 10 % glycerol.
- 储存条件
- -20 °C,-80 °C
- 储存方法
-
Short Term Storage: -20°C
Long Term Storage: -80°C
Stable for at least 6 months after receipt when stored at -80°C. - 有效期
- 6 months
-
- 抗原
- PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
- 别名
- PARP-3 [ARTD3] (PARP3 产品)
- 别名
- ADPRT-3 Protein, PARP-3 Protein, PM38 Protein, Adprtl3 Protein, fj17c06 Protein, wu:fj17c06 Protein, zgc:66157 Protein, PARP3 Protein, parp3 Protein, ADPRT3 Protein, ADPRTL2 Protein, ADPRTL3 Protein, ARTD3 Protein, IRT1 Protein, PADPRT-3 Protein, A930002C11Rik Protein, AW990611 Protein, Adprt3 Protein, pADPRT-3 Protein, seed maturation protein PM38 Protein, poly (ADP-ribose) polymerase family, member 3 Protein, poly(ADP-ribose) polymerase family member 3 Protein, poly(ADP-ribose) polymerase family member 3 L homeolog Protein, PARP3 Protein, parp3 Protein, parp3.L Protein, Parp3 Protein
- 背景
- PARP-3 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
- UniProt
- Q9Y6F1
-