NMNAT3 Protein (AA 1-252) (His tag)
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- 抗原 See all NMNAT3 蛋白
- NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 1-252
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This NMNAT3 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 人
- 产品特性
- Human full-length NMNAT3 (aa 1-252) is fused at the N-terminus to a His-tag.
- 纯度
- >95 % (SDS-PAGE)
- Top Product
- Discover our top product NMNAT3 蛋白
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Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3) (AA 1-252) protein (His tag)
NMNAT3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3) (AA 1-215) protein (GST tag)NMNAT3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3) (AA 116-215) protein (GST tag)NMNAT3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3) (AA 1-215), (Isoform 2) protein (His-SUMO Tag)NMNAT3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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>2U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1μmol of NAD+ per min.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In 50 mM TRIS-HCl, pH 8.0, containing 300 mM sodium chloride, 1 mM DTT and 10 % glycerol.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.
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- 抗原
- NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))
- 别名
- NMNAT3 (NMNAT3 产品)
- 别名
- PNAT-3 Protein, PNAT3 Protein, 4933408N02Rik Protein, nicotinamide nucleotide adenylyltransferase 3 Protein, si:ch73-170l17.1 Protein, Nmnat3 Protein, NMNAT3 Protein, si:ch73-170l17.1 Protein
- 背景
- Mitochondrial NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Can use tiazofurin monophosphate as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD(+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.
- 分子量
- ~27kDa (monomer)
- UniProt
- Q96T66
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