NAPRT1 Protein (His tag)
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- 抗原 See all NAPRT1 (NAPRT) 蛋白
- NAPRT1 (NAPRT) (Nicotinate phosphoribosyltransferase (NAPRT))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This NAPRT1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 人
- 产品特性
- Human NAPRTase is fused at the N-terminus to a His-tag.
- 纯度
- >98 % (SDS-PAGE)
- Top Product
- Discover our top product NAPRT 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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~0.27 U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1μmol nicotinic acid mononucleotide (NaMN) per min.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In 50 mM HEPES/KOH pH 7.5 containing 300 mM potassium chloride and 10 mM DTT.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
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Short Term Storage: -20°C
Long Term Storage: -80°C
Stable for at least 6 months after receipt when stored at -80°C. - 有效期
- 6 months
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- 抗原
- NAPRT1 (NAPRT) (Nicotinate phosphoribosyltransferase (NAPRT))
- 别名
- NAPRTase (NAPRT 产品)
- 别名
- PP3856 Protein, 9130210N20Rik Protein, zgc:77870 Protein, nicotinate phosphoribosyltransferase Protein, NAPRT Protein, Naprt Protein, naprt Protein
- 背景
- Human nicotinate phosphoribosyltransferase (NAPRTase) is localized in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress and water-soluble vitamin metabolic process. It functions by catalyzing the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) and is essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. It is a crucial factor in the NAD+ biosynthesis pathway. Catalytic activity: Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.
- 分子量
- ~58.0kDa
- UniProt
- Q6XQN6
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