C19ORF80 Protein (Fc Tag)
C19ORF80
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
>90 % (SDS-PAGE)
SDS
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- 抗原 See all C19ORF80 蛋白
- C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This C19ORF80 protein is labelled with Fc Tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 小鼠
- 产品特性
- Mouse betatrophin (22-198) is fused at the C-terminus to the Fc portion of human IgG1.
- 纯度
- >90 % (SDS-PAGE)
- 内毒素水平
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product C19ORF80 蛋白
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Chromosome 19 Open Reading Frame 80 (C19ORF80) (AA 22-198) protein (His tag)
C19ORF80 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chromosome 19 Open Reading Frame 80 (C19ORF80) protein (GST tag)C19ORF80 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 100 μL sterile water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS + 0.02 % CHAPS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))
- 别名
- Betatrophin (C19ORF80 产品)
- 别名
- ANGPTL8 Protein, PRO1185 Protein, PVPA599 Protein, RIFL Protein, TD26 Protein, angiopoietin like 8 Protein, ANGPTL8 Protein
- 背景
- Betatrophin (RIFL, Lipasin, Angiopoietin-like protein 8 (ANGPTL8)) is a newly discovered secreted protein of 198 aa that was proposed to promote beta cell proliferation and improve glucose tolerance in mice. Betatrophin may also function in inhibition of lipase activity and on serum triglyceride regulation. Betatrophin is expressed in the liver and in white and brown adipose tissue of mice. In humans, betatrophin is found to be predominantly expressed in the liver. Betatrophin levels are reduced by fasting and are elevated upon insulin resistance and during pregnancy. Betatrophin, according to preliminary data could bind to the macrophage receptor Marco and also to RTN4R, a neuronal receptor. Recently, a study using ANGPTL8 KO mice showed that ANGPTL8/Betatrophin does not play a role in beta cell proliferation nor in glycemic control as previously thought, but regulates plasma triglyceride levels.
- 分子量
- ~50kDa
- UniProt
- Q8R1L8
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