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WFS1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

WFS1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2735628
发货至: 中国
  • 抗原 See all WFS1 蛋白
    WFS1 (Wolfram Syndrome 1 (WFS1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 5
    • 2
    • 2
    资源
    • 6
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This WFS1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Wolframin / WFS1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product WFS1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    WFS1 (Wolfram Syndrome 1 (WFS1))
    别名
    Wolframin,wfs1 (WFS1 产品)
    别名
    WFRS Protein, WFS Protein, WFSL Protein, CG4917 Protein, Dmel\\CG4917 Protein, GB15257 Protein, WFS1 Protein, AI481085 Protein, wolframin Protein, wfs1 Protein, wolframin ER transmembrane glycoprotein Protein, wolfram syndrome 1 Protein, wolframin Protein, Wolfram syndrome 1 (wolframin) L homeolog Protein, Wfs1 Protein, WFS1 Protein, wfs1 Protein, LOC552818 Protein, CpipJ_CPIJ013087 Protein, wfs1.L Protein
    背景
    This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.
    分子量
    100.1 kDa
    NCBI登录号
    NP_005996
    途径
    Sensory Perception of Sound, Carbohydrate Homeostasis, ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
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