Uromodulin Protein (UMOD) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
UMOD
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
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- 抗原 See all Uromodulin (UMOD) 蛋白
- Uromodulin (UMOD)
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Uromodulin protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Uromodulin (UMOD) (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product UMOD 蛋白
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Uromodulin (UMOD) (AA 1-611) protein (GST tag)
UMOD 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Uromodulin (UMOD) (AA 25-120) protein (GST tag)UMOD 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- Uromodulin (UMOD)
- Abstract
- UMOD 产品
- 别名
- ADMCKD2 Protein, FJHN Protein, HNFJ Protein, HNFJ1 Protein, MCKD2 Protein, THGP Protein, THP Protein, urehr4 Protein, uromodulin Protein, UMOD Protein, Umod Protein
- 背景
- The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.
- 分子量
- 67.1 kDa
- NCBI登录号
- NP_003352
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