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RENT2/UPF2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

UPF2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2735035
发货至: 中国
  • 抗原 See all RENT2/UPF2 (UPF2) products
    RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    资源
    • 1
    HEK-293 Cells
    标记
    This RENT2/UPF2 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human UPF2 / RENT2 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
    别名
    Upf2,rent2 (UPF2 产品)
    别名
    HUPF2 Protein, RENT2 Protein, smg-3 Protein, UPF2, regulator of nonsense mediated mRNA decay Protein, UPF2 regulator of nonsense transcripts homolog (yeast) Protein, UPF2 Protein, Upf2 Protein, upf2 Protein
    背景
    This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene both variants encode the same protein.
    分子量
    147.6 kDa
    NCBI登录号
    NP_542166
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