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UNC45B Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

UNC45B 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2735016
发货至: 中国
  • 抗原 See all UNC45B 蛋白
    UNC45B (Unc-45 Homolog B (UNC45B))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    资源
    • 1
    • 1
    HEK-293 Cells
    标记
    This UNC45B protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human UNC45B (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product UNC45B 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    UNC45B (Unc-45 Homolog B (UNC45B))
    别名
    Unc45b (UNC45B 产品)
    别名
    MGC80931 Protein, cmya4 Protein, AA445617 Protein, Cmya4 Protein, D230041A13Rik Protein, Unc45 Protein, CMYA4 Protein, SMUNC45 Protein, UNC45 Protein, Unc-45B Protein, cb393 Protein, unc45r Protein, wu:fa05a03 Protein, wu:fa10f03 Protein, wu:fb37f02 Protein, wu:fb96f06 Protein, wu:fc10f04 Protein, unc-45 myosin chaperone B S homeolog Protein, unc-45 myosin chaperone B Protein, unc45b.S Protein, unc45b Protein, UNC45B Protein, Unc45b Protein
    背景
    This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.
    分子量
    103.6 kDa
    NCBI登录号
    NP_775259
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