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UNC13D Protein (Myc-DYKDDDDK Tag)

UNC13D 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2735014
发货至: 中国
  • 抗原 See all UNC13D 蛋白
    UNC13D (Unc-13 Homolog D (UNC13D))
    蛋白类型
    Recombinant
    宿主
    资源
    • 1
    • 1
    HEK-293 Cells
    标记
    This UNC13D protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human UNC13D protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product UNC13D 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    UNC13D (Unc-13 Homolog D (UNC13D))
    别名
    Unc13d (UNC13D 产品)
    别名
    FHL3 Protein, HLH3 Protein, HPLH3 Protein, Munc13-4 Protein, UNC13D Protein, 2610108D09Rik Protein, Jinx Protein, mFLJ00067 Protein, Unc13h4 Protein, BIGH3 Protein, CDB1 Protein, CDG2 Protein, CDGG1 Protein, CSD Protein, CSD1 Protein, CSD2 Protein, CSD3 Protein, EBMD Protein, LCD1 Protein, unc-13 homolog D Protein, unc-13 homolog D (C. elegans) Protein, transforming growth factor beta induced Protein, UNC13D Protein, Unc13d Protein, TGFBI Protein, unc13d Protein, un13d Protein
    背景
    This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
    分子量
    123.1 kDa
    NCBI登录号
    NP_954712
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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