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TYROBP Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

TYROBP 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2734711
发货至: 中国
  • 抗原 See all TYROBP 蛋白
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    资源
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This TYROBP protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human TYROBP / DAP12 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TYROBP 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    别名
    Tyrobp,dap12 (TYROBP 产品)
    别名
    TYROBP Protein, DAP12 Protein, tyrpbp Protein, Karap Protein, KARAP Protein, PLOSL Protein, Ly83 Protein, dap12 Protein, TYRO protein tyrosine kinase binding protein Protein, Tyro protein tyrosine kinase binding protein Protein, TYROBP Protein, tyrobp Protein, Tyrobp Protein
    背景
    This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.
    分子量
    9.3 kDa
    NCBI登录号
    NP_003323
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