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TUBB3 Protein (Myc-DYKDDDDK Tag)

TUBB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2734576
发货至: 中国
  • 抗原 See all TUBB3 蛋白
    TUBB3 (Tubulin, beta 3 (TUBB3))
    蛋白类型
    Recombinant
    宿主
    • 6
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    资源
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    HEK-293 Cells
    标记
    This TUBB3 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human TUBB3 / TUBB4 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TUBB3 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Huang, Shao, Qu, Yang, Dwyer, Liu: "Coordinated interaction of Down syndrome cell adhesion molecule and deleted in colorectal cancer with dynamic TUBB3 mediates Netrin-1-induced axon branching." in: Neuroscience, Vol. 293, pp. 109-22, (2015) (PubMed).

    Soufi, Garcia, Jaroszewicz, Osman, Pellegrini, Zaret: "Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming." in: Cell, Vol. 161, Issue 3, pp. 555-68, (2015) (PubMed).

    Wang, Reece, Yang: "Oxidative stress is responsible for maternal diabetes-impaired transforming growth factor beta signaling in the developing mouse heart." in: American journal of obstetrics and gynecology, Vol. 212, Issue 5, pp. 650.e1-11, (2015) (PubMed).

    Gallardo, Martínez-Hernández, Titulaer, Huijbers, Martínez, Ramos, Querol, Díaz-Manera, Rojas-García, Hayworth, Verschuuren, Balice-Gordon, Dalmau, Illa: "Cortactin autoantibodies in myasthenia gravis." in: Autoimmunity reviews, Vol. 13, Issue 10, pp. 1003-7, (2014) (PubMed).

    Qu, Dwyer, Shao, Yang, Huang, Liu: "Direct binding of TUBB3 with DCC couples netrin-1 signaling to intracellular microtubule dynamics in axon outgrowth and guidance." in: Journal of cell science, Vol. 126, Issue Pt 14, pp. 3070-81, (2013) (PubMed).

    Hou, Li, Zhang, Liu, Guan, Li, Zhao, Ye, Yang, Liu, Ge, Xu, Zhang, Zhao, Deng: "Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds." in: Science (New York, N.Y.), Vol. 341, Issue 6146, pp. 651-4, (2013) (PubMed).

  • 抗原
    TUBB3 (Tubulin, beta 3 (TUBB3))
    别名
    Tubb3,tubb4 (TUBB3 产品)
    别名
    CDCBM Protein, CFEOM3A Protein, TUBB4 Protein, beta-4 Protein, TUBB3 Protein, 3200002H15Rik Protein, M(beta)3 Protein, M(beta)6 Protein, tubb3 Protein, tubulin beta 3 class III Protein, tubulin, beta 3 class III Protein, tubulin beta 3 class III L homeolog Protein, beta-tubulin 3 Protein, tubulin beta-3 chain Protein, beta tubulin 3 Protein, TUBB3 Protein, Tubb3 Protein, tubb3 Protein, tubb3.L Protein, LOC100581245 Protein, tub3 Protein
    背景
    This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.
    分子量
    50.3 kDa
    NCBI登录号
    NP_006077
    途径
    Microtubule Dynamics, M Phase
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