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TRIM68 Protein (Myc-DYKDDDDK Tag)

TRIM68 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2734291
发货至: 中国
  • 抗原 See all TRIM68 蛋白
    TRIM68 (Tripartite Motif Containing 68 (TRIM68))
    蛋白类型
    Recombinant
    宿主
    • 2
    • 1
    资源
    • 2
    • 1
    HEK-293 Cells
    标记
    This TRIM68 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human TRIM68 / RNF137 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TRIM68 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    TRIM68 (Tripartite Motif Containing 68 (TRIM68))
    别名
    Trim68,rnf137 (TRIM68 产品)
    别名
    GC109 Protein, RNF137 Protein, SS-56 Protein, SS56 Protein, AI894158 Protein, F730114J12Rik Protein, Rnf137 Protein, TRIM68 Protein, tripartite motif containing 68 Protein, tripartite motif-containing 68 Protein, E3 ubiquitin-protein ligase TRIM68 Protein, TRIM68 Protein, Trim68 Protein, LOC100053519 Protein
    背景
    This gene encodes a member of the tripartite motif-containing protein family, whose members are characterized by a 'really interesting new gene' (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family function as E3 ubiquitin ligases and are involved in a broad range of biological processes. This gene regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, this gene participates in viral defense regulation as a negative regulator of interferon-beta. Alternative splicing results in multiple transcript variants.
    分子量
    56.1 kDa
    NCBI登录号
    NP_060543
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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