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STAM Protein (Myc-DYKDDDDK Tag)

STAM 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2732750
发货至: 中国
  • 抗原 See all STAM 蛋白
    STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 2
    • 1
    • 1
    资源
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This STAM protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human STAM1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product STAM 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
    别名
    Stam1 (STAM 产品)
    别名
    STAM-1 Protein, STAM1 Protein, wu:fv75b10 Protein, zgc:55725 Protein, RGD1564499 Protein, signal transducing adaptor molecule Protein, signal transducing adapter molecule 1 Protein, Signal transducing adapter molecule 1 Protein, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 Protein, STAM Protein, CpipJ_CPIJ003516 Protein, Tsp_03939 Protein, stam-1 Protein, Stam Protein, stam Protein
    背景
    Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. [UniProtKB/Swiss-Prot Function]
    分子量
    59 kDa
    NCBI登录号
    NP_003464
    途径
    EGFR Signaling Pathway, EGFR Downregulation
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