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SPHK1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

SPHK1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2732578
发货至: 中国
  • 抗原 See all SPHK1 蛋白
    SPHK1 (Sphingosine Kinase 1 (SPHK1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 9
    • 2
    • 2
    • 1
    资源
    • 2
    • 2
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    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This SPHK1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Sphingosine kinase 1 (SPHK1) (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SPHK1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    SPHK1 (Sphingosine Kinase 1 (SPHK1))
    Abstract
    SPHK1 产品
    别名
    CG1747 Protein, Dmel\\CG1747 Protein, SK1 Protein, Sphk1 Protein, SPHK1 Protein, F18E5.160 Protein, F18E5_160 Protein, sphingosine kinase 1 Protein, SPHK Protein, 1110006G24Rik Protein, Sk1 Protein, Spk1 Protein, Sphingosine kinase 1 Protein, sphingosine kinase 1 Protein, sphingosine kinase 1 L homeolog Protein, Sk1 Protein, SPHK1 Protein, sphk1.L Protein, Sphk1 Protein
    背景
    The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量
    43.8 kDa
    NCBI登录号
    NP_068807
    途径
    VEGF Signaling
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