PTTG1 Protein (Myc-DYKDDDDK Tag)
-
- 抗原 See all PTTG1 蛋白
- PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This PTTG1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human Securin / PTTG1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTTG1 蛋白
-
Pituitary Tumor-Transforming 1 (PTTG1) (AA 1-202) protein (His-IF2DI Tag)
PTTG1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Pituitary Tumor-Transforming 1 (PTTG1) (AA 1-202) protein (His tag)PTTG1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % by SDS - PAGE SDS
Pituitary Tumor-Transforming 1 (PTTG1) (AA 1-202) protein (GST tag)PTTG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Pituitary Tumor-Transforming 1 (PTTG1) (AA 1-100) protein (GST tag)PTTG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Pituitary Tumor-Transforming 1 (PTTG1) (AA 2-202) protein (His tag)Crystallography grade PTTG1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Pituitary Tumor-Transforming 1 (PTTG1) (AA 2-199) protein (His tag)Crystallography grade PTTG1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
- 别名
- Securin,pttg1 (PTTG1 产品)
- 别名
- EAP1 Protein, HPTTG Protein, PTTG Protein, TUTR1 Protein, PTTG1 Protein, securin Protein, AW555095 Protein, C87862 Protein, Pttg Protein, Pttg3 Protein, Securin Protein, Protein Cut2 Protein, pituitary tumor-transforming 1 Protein, pituitary tumor-transforming gene 1 Protein, securin, sister chromatid separation inhibitor Protein, PTTG1 Protein, Pttg1 Protein, cut2 Protein
- 背景
- The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. Three transcript variants encoding the same protein have been found for this gene.
- 分子量
- 21.8 kDa
- NCBI登录号
- NP_004210
-
