SAV1 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all SAV1 蛋白
- SAV1 (Salvador Homolog 1 (SAV1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SAV1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human SAV1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SAV1 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- SAV1 (Salvador Homolog 1 (SAV1))
- 别名
- Sav1 (SAV1 产品)
- 别名
- SAV Protein, WW45 Protein, WWP4 Protein, 1700040G09Rik Protein, Salv Protein, Sav Protein, Wwp3 Protein, Wwp4 Protein, salvador family WW domain containing protein 1 Protein, salvador family WW domain containing 1 Protein, SAV1 Protein, Sav1 Protein
- 背景
- WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
- 分子量
- 44.5 kDa
- NCBI登录号
- NP_068590
- 途径
- Stem Cell Maintenance
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