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RPE65 Protein (Myc-DYKDDDDK Tag)

RPE65 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2731119
发货至: 中国
  • 抗原 See all RPE65 蛋白
    RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 3
    • 2
    • 1
    资源
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This RPE65 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human RPE65 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RPE65 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
    别名
    Rpe65 (RPE65 产品)
    别名
    LCA2 Protein, RP20 Protein, mRPE65 Protein, rd12 Protein, sRPE65 Protein, 65kDa Protein, A930029L06Rik Protein, Mord1 Protein, DRPE65 Protein, RPE65 Protein, anon-WO0148162.1 Protein, anon-WO0148163.1 Protein, beta-diox Protein, DmelCG9347 Protein, CG9347 Protein, MGC52887 Protein, MGC154296 Protein, MGC85437 Protein, rpe65 Protein, RPE56c Protein, si:ch211-198n5.12 Protein, 13cIMH Protein, RPE56b Protein, rpepb Protein, si:ch211-198n5.5 Protein, wu:fc74c09 Protein, zgc:110538 Protein, RPE56a Protein, rpepa Protein, zgc:73213 Protein, RPE65, retinoid isomerohydrolase Protein, retinal pigment epithelium 65 Protein, neither inactivation nor afterpotential B Protein, retinal pigment epithelium-specific protein 65kDa S homeolog Protein, retinal pigment epithelium-specific protein 65kDa L homeolog Protein, RPE65 homolog Protein, retinal pigment epithelium-specific protein 65kDa Protein, retinal pigment epithelium-specific protein 65c Protein, retinal pigment epithelium-specific protein 65b Protein, retinal pigment epithelium-specific protein 65a Protein, RPE65 Protein, Rpe65 Protein, ninaB Protein, rpe65.S Protein, rpe65.L Protein, rpe65 Protein, rpe65c Protein, rpe65b Protein, rpe65a Protein
    背景
    This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa.
    分子量
    60.8 kDa
    NCBI登录号
    NP_000320
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