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RASD2 Protein (Myc-DYKDDDDK Tag)

RASD2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2730533
发货至: 中国
  • 抗原 See all RASD2 蛋白
    RASD2 (RASD Family, Member 2 (RASD2))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 2
    • 2
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This RASD2 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human RASD2 / TEM2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RASD2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    RASD2 (RASD Family, Member 2 (RASD2))
    别名
    Rasd2,tem2 (RASD2 产品)
    别名
    RASD2 Protein, MGC:4834 Protein, Rhes Protein, TEM2 Protein, 4930526B11Rik Protein, AU045414 Protein, TEM-2 Protein, RASD family member 2 Protein, RASD family, member 2 Protein, RASD2 Protein, Rasd2 Protein
    背景
    This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients.
    分子量
    30.2 kDa
    NCBI登录号
    NP_055125
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