RASA1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all RASA1 蛋白
- RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This RASA1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human RASA1 / RasGAP (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RASA1 蛋白
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RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 1-870) protein (GST tag)
RASA1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 948-1047) protein (GST tag)RASA1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 1-1047) protein (Strep Tag)Crystallography grade RASA1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
- 别名
- Rasa1,rasgap (RASA1 产品)
- 别名
- CG9209 Protein, D-RasGAP Protein, Dmel\\CG9209 Protein, RAS-GAP Protein, RasGAP Protein, RasGap Protein, rasGap Protein, CM-AVM Protein, CMAVM Protein, GAP Protein, PKWS Protein, RASA Protein, RASGAP Protein, p120GAP Protein, p120RASGAP Protein, GAPX Protein, Rasa Protein, Gap Protein, vacuolar peduncle Protein, RAS p21 protein activator 1 Protein, vap Protein, RASA1 Protein, Rasa1 Protein
- 背景
- The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.
- 分子量
- 116.2 kDa
- NCBI登录号
- NP_002881
- 途径
- Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
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