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RAB8A Protein (Myc-DYKDDDDK Tag)

RAB8A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2730373
发货至: 中国
  • 抗原 See all RAB8A 蛋白
    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
    蛋白类型
    Recombinant
    宿主
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    资源
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    HEK-293 Cells
    标记
    This RAB8A protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human RAB8A protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RAB8A 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
    别名
    Rab8a (RAB8A 产品)
    别名
    rab8A Protein, DDBDRAFT_0206521 Protein, DDBDRAFT_0214885 Protein, DDB_0206521 Protein, DDB_0214885 Protein, HSH2D Protein, mel Protein, rab8 Protein, c-mel Protein, MEL Protein, RAB8 Protein, zgc:162699 Protein, AA409338 Protein, Mel Protein, Rab8 Protein, rab8A protein Protein, Rab GTPase Protein, RAB8A, member RAS oncogene family Protein, RAB8A, member RAS oncogene family S homeolog Protein, rab8A Protein, RAB8A Protein, rab8a Protein, rab8a.S Protein, Rab8a Protein
    背景
    The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97 % , 96 %, and 51 % similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.
    分子量
    23.5 kDa
    NCBI登录号
    NP_005361
    途径
    M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
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