PTRF Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all PTRF 蛋白
- PTRF (Polymerase I and Transcript Release Factor (PTRF))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PTRF protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human PTRF protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTRF 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PTRF (Polymerase I and Transcript Release Factor (PTRF))
- 别名
- Ptrf (PTRF 产品)
- 别名
- MGC53017 Protein, MGC89141 Protein, PTRF Protein, fd20g07 Protein, ptrf Protein, wu:fd20g07 Protein, zgc:162917 Protein, CAVIN Protein, CAVIN1 Protein, CGL4 Protein, cavin-1 Protein, 2310075E07Rik Protein, AW546441 Protein, Cav-p60 Protein, Cavin Protein, caveolae associated protein 1 L homeolog Protein, polymerase I and transcript release factor Protein, caveolae associated protein 1 Protein, caveolae associated protein 1b Protein, caveolae associated 1 Protein, cavin1.L Protein, PTRF Protein, cavin1 Protein, CAVIN1 Protein, cavin1b Protein, Cavin1 Protein
- 背景
- This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.
- 分子量
- 43.3 kDa
- NCBI登录号
- NP_036364
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