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PTPN21 Protein (Myc-DYKDDDDK Tag)

PTPN21 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2730115
发货至: 中国
  • 抗原 See all PTPN21 蛋白
    PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 3
    • 1
    • 1
    • 1
    资源
    • 3
    • 2
    HEK-293 Cells
    标记
    This PTPN21 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human PTPN21 / PTPD1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PTPN21 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
    别名
    Ptpn21,ptpd1 (PTPN21 产品)
    别名
    PTPD1 Protein, PTPRL10 Protein, Ptp2E Protein, protein tyrosine phosphatase, non-receptor type 21 Protein, PTPN21 Protein, Ptpn21 Protein
    背景
    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.
    分子量
    133.1 kDa
    NCBI登录号
    NP_008970
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