PSTPIP1 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all PSTPIP1 蛋白
- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PSTPIP1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human PSTPIP1 / CD2BP1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PSTPIP1 蛋白
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Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (AA 1-416) protein (His tag)
PSTPIP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (AA 1-416) protein (GST tag)PSTPIP1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (AA 148-247) protein (GST tag)PSTPIP1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (AA 1-416) protein (Strep Tag)Crystallography grade PSTPIP1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (AA 1-415) protein (Strep Tag)Crystallography grade PSTPIP1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
- 别名
- Pstpip1,cd2bp1 (PSTPIP1 产品)
- 别名
- cd2bp1 Protein, cd2bp1l Protein, cd2bp1s Protein, h-pip Protein, papas Protein, pstpip Protein, PSTPIP1 Protein, CD2BP1 Protein, CD2BP1L Protein, CD2BP1S Protein, H-PIP Protein, PAPAS Protein, PSTPIP Protein, def-2 Protein, proline-serine-threonine phosphatase interacting protein 1 Protein, proline-serine-threonine phosphatase interacting protein 1 S homeolog Protein, proline-serine-threonine phosphatase-interacting protein 1 Protein, PSTPIP1 Protein, pstpip1.S Protein, pstpip1 Protein, Pstpip1 Protein
- 背景
- This gene encodes a cytoskeletal protein that is highly expressed in hemopoietic tissues. This protein functions via its interaction with several different proteins involved in cytoskeletal organization and inflammatory processes. It binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, downregulating CD2-triggered adhesion. It binds PEST-type protein tyrosine phosphatases (PTP) and directs them to c-Abl kinase to mediate c-Abl dephosphorylation, thereby, regulating c-Abl activity. It also interacts with pyrin, which is found in association with the cytoskeleton in myeloid/monocytic cells and modulates immunoregulatory functions. Mutations in this gene are associated with PAPA (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) syndrome. It is hypothesized that the disease-causing mutations compromise physiologic signaling necessary for the maintenance of a proper inflammatory response.
- 分子量
- 47.4 kDa
- NCBI登录号
- NP_003969
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