PLEKHM2 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all PLEKHM2 蛋白
- PLEKHM2 (Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PLEKHM2 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human PLEKHM2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PLEKHM2 蛋白
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Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2) (AA 1-440) protein (GST tag)
PLEKHM2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2) (AA 1-1019) protein (Strep Tag)Crystallography grade PLEKHM2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2) (AA 1-1018) protein (Strep Tag)Crystallography grade PLEKHM2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PLEKHM2 (Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2))
- 别名
- Plekhm2 (PLEKHM2 产品)
- 别名
- zgc:194971 Protein, RP11-169K16.1 Protein, SKIP Protein, 2310034J19Rik Protein, AI854247 Protein, mKIAA0842 Protein, pleckstrin homology and RUN domain containing M2 Protein, pleckstrin homology domain containing, family M (with RUN domain) member 2 Protein, PLEKHM2 Protein, plekhm2 Protein, Plekhm2 Protein
- 背景
- This gene encodes a protein that binds the plus-end directed microtubule motor protein kinesin, together with the lysosomal GTPase Arl8, and is required for lysosomes to distribute away from the microtubule-organizing center. The encoded protein belongs to the multisubunit BLOC-one-related complex that regulates lysosome positioning. It binds a Salmonella effector protein called Salmonella induced filament A and is a critical host determinant in Salmonella pathogenesis. It has a domain architecture consisting of an N-terminal RPIP8, UNC-14, and NESCA (RUN) domain that binds kinesin-1 as well as the lysosomal GTPase Arl8, and a C-terminal pleckstrin homology domain that binds the Salmonella induced filament A effector protein. Naturally occurring mutations in this gene lead to abnormal localization of lysosomes, impaired autophagy flux and are associated with recessive dilated cardiomyopathy and left ventricular noncompaction.
- 分子量
- 112.6 kDa
- NCBI登录号
- NP_055979
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