PLCE1 Protein (Myc-DYKDDDDK Tag)
PLCE1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
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- 抗原 See all PLCE1 蛋白
- PLCE1 (Phospholipase C, epsilon 1 (PLCE1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PLCE1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human PLCE1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PLCE1 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PLCE1 (Phospholipase C, epsilon 1 (PLCE1))
- 别名
- Plce1 (PLCE1 产品)
- 别名
- PLCE1 Protein, NPHS3 Protein, PLCE Protein, PPLC Protein, 4933403A21Rik Protein, PLCepsilon Protein, Plce Protein, mKIAA1516 Protein, phospholipase C, epsilon 1 Protein, phospholipase C epsilon 1 Protein, PLCE1 Protein, plce1 Protein, Plce1 Protein
- 背景
- This gene encodes a phospholipase enzyme that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). These second messengers subsequently regulate various processes affecting cell growth, differentiation, and gene expression. This enzyme is regulated by small monomeric GTPases of the Ras and Rho families and by heterotrimeric G proteins. In addition to its phospholipase C catalytic activity, this enzyme has an N-terminal domain with guanine nucleotide exchange (GEF) activity. Mutations in this gene cause early-onset nephrotic syndrome characterized by proteinuria, edema, and diffuse mesangial sclerosis or focal and segmental glomerulosclerosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]
- 分子量
- 258.5 kDa
- NCBI登录号
- NP_057425
- 途径
- EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
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