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FXYD1 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

FXYD1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2728859
发货至: 中国
  • 抗原 See all FXYD1 蛋白
    FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant A
    宿主
    • 1
    • 1
    资源
    • 2
    HEK-293 Cells
    标记
    This FXYD1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Phospholemman (transcript variant a) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FXYD1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))
    别名
    Phospholemman (FXYD1 产品)
    别名
    PLM Protein, 0610012C17Rik Protein, 1110006M24Rik Protein, Plm Protein, Pml Protein, FXYD domain containing ion transport regulator 1 Protein, FXYD domain-containing ion transport regulator 1 Protein, FXYD1 Protein, Fxyd1 Protein
    背景
    This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature.
    分子量
    8.3 kDa
    NCBI登录号
    NP_005022
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