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PCBP2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

PCBP2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2728353
发货至: 中国
  • 抗原 See all PCBP2 蛋白
    PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 7
    • 1
    资源
    • 4
    • 2
    • 2
    HEK-293 Cells
    标记
    This PCBP2 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human PCBP2 / hnRNP-E2 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PCBP2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Školáková, Foldynová-Trantírková, Bednářová, Fiala, Vorlíčková, Trantírek: "Unique C. elegans telomeric overhang structures reveal the evolutionarily conserved properties of telomeric DNA." in: Nucleic acids research, Vol. 43, Issue 9, pp. 4733-45, (2015) (PubMed).

  • 抗原
    PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
    别名
    Pcbp2,hnrnp-e2 (PCBP2 产品)
    别名
    HNRNPE2 Protein, HNRPE2 Protein, hnRNP-E2 Protein, AW412548 Protein, Hnrpx Protein, alphaCP-2 Protein, PCBP3 Protein, fb36h02 Protein, wu:fb36h02 Protein, zgc:55964 Protein, PCBP2 Protein, poly(rC) binding protein 2 Protein, poly(rC) binding protein 2 L homeolog Protein, PCBP2 Protein, Pcbp2 Protein, pcbp2 Protein, pcbp2.L Protein
    背景
    The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量
    38.5 kDa
    NCBI登录号
    NP_005007
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