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PTH 蛋白

PTH 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, STD, AbP, PI Active
产品编号 ABIN2728243
发货至: 中国
  • 抗原 See all PTH 蛋白
    PTH (Parathyroid Hormone (PTH))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
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    资源
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    大肠杆菌(E. Coli)
    应用范围
    Functional Studies (Func), Standard (STD), Antibody Production (AbP), Protein Interaction (PI)
    特异性
    Optimal preservation of protein structure, post-translational modifications and functions.
    产品特性
    • Recombinant human Parathyroid hormone / PTH protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    纯度
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    内毒素水平
    < 0.1 EU per μg protein as determined by LAL test
    Biological Activity Comment
    Specific Activity of 1.0 x 104 IU/mg as calculated by the UMR106 cell/cAMP method.
    Top Product
    Discover our top product PTH 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    限制
    仅限研究用
  • 缓冲液
    Lyophilized from a 0.2 μM filtered solution of 10 mM HAc-NaAc, 150 mM NaCl, 5 % Mannitol, pH 4.0. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    PTH (Parathyroid Hormone (PTH))
    别名
    Parathyroid Hormone,pth (PTH 产品)
    别名
    PTH1 Protein, Pthp Protein, PTH-(1-84) Protein, Pth1 Protein, Pthr1 Protein, PTH Protein, parathyroid hormone Protein, parathyroid hormone S homeolog Protein, PTH Protein, Pth Protein, pth.S Protein
    物质类
    Hormone
    背景
    This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants.
    分子量
    9.4 kDa
    NCBI登录号
    NP_000306
    途径
    cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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