NUB1 Protein (Myc-DYKDDDDK Tag)
-
- 抗原 See all NUB1 蛋白
- NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This NUB1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human NUB1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NUB1 蛋白
-
Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 1-601) protein (GST tag)
NUB1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 503-601) protein (GST tag)NUB1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 1-615) protein (Strep Tag)Crystallography grade NUB1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 1-614) protein (Strep Tag)Crystallography grade NUB1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
- 别名
- Nub1 (NUB1 产品)
- 别名
- BS4 Protein, NYREN18 Protein, NUB1L Protein, 4931404D21Rik Protein, 6330412F12Rik Protein, NY-REN-18 Protein, negative regulator of ubiquitin-like proteins 1 Protein, negative regulator of ubiquitin like proteins 1 Protein, Nub1 Protein, NUB1 Protein
- 背景
- This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson&aposs disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of this gene results in multiple transcript variants.
- 分子量
- 68.9 kDa
- NCBI登录号
- NP_057202
-
