GTPase NRas Protein (NRAS) (Myc-DYKDDDDK Tag)
Quick Overview for GTPase NRas Protein (NRAS) (Myc-DYKDDDDK Tag) (ABIN2727605)
抗原
See all GTPase NRas (NRAS) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This GTPase NRas protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human NRAS protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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GTPase NRas (NRAS) (AA 90-189) protein (GST tag)
NRAS 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
GTPase NRas (NRAS) (AA 1-189) protein (GST tag)NRAS 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
GTPase NRas (NRAS) (AA 1-186) proteinNRAS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure SDS
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- GTPase NRas (NRAS)
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别名
- Nras
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背景
- This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
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分子量
- 21 kDa
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NCBI登录号
- NP_002515
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途径
- p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
抗原
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