NR0B2 Protein (His tag)
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- 抗原 See all NR0B2 蛋白
- NR0B2 (Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This NR0B2 protein is labelled with His tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human NR0B2 (full length, N-term HIS tag) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NR0B2 蛋白
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Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) (AA 1-257) protein (GST tag)
NR0B2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) (AA 1-257) protein (Strep Tag)Crystallography grade NR0B2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2) (AA 1-260) protein (Strep Tag)Crystallography grade NR0B2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the N-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- NR0B2 (Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
- 别名
- Nr0b2 (NR0B2 产品)
- 别名
- SHP Protein, SHP1 Protein, SHP-1 Protein, Shp1 Protein, Shp Protein, NR0B2-A Protein, Nr0b2 Protein, SHP-A Protein, gb:bc058069 Protein, nuclear receptor subfamily 0 group B member 2 Protein, nuclear receptor subfamily 0, group B, member 2 Protein, nuclear receptor subfamily 0, group B, member 2a Protein, NR0B2 Protein, Nr0b2 Protein, nr0b2a Protein
- 背景
- The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function.
- 分子量
- 28.1 kDa
- NCBI登录号
- NP_068804
- 途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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